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Post authorisation influenza vaccine effectiveness against influenza associated hospitalisation with laboratory confirmed influenza among adults in Europe

Identifieur interne : 000039 ( France/Analysis ); précédent : 000038; suivant : 000040

Post authorisation influenza vaccine effectiveness against influenza associated hospitalisation with laboratory confirmed influenza among adults in Europe

Auteurs : Marc Rondy [France]

Source :

RBID : Hal:tel-01635265

Descripteurs français

English descriptors

Abstract

Our objective was to measure seasonal influenza vaccine effectiveness (IVE) against hospitalisation with laboratory-confirmed influenza in Europe among adults. Between 2011 and 2017, we coordinated a multicenter case-control study in 29 hospitals in 12 countries. We pooled and analysed the data after every season. Between 2011-12 and 2016-17, we recruited 3436 influenza cases and 5969 controls. Pooled across seasons, IVE against any influenza was 26%; 40% patients aged 18-64 yeas, 25% among those aged 65-79 years, and 23% among those aged ≥80 years. Season specific IVE ranged between 15% in 2016-17 and 44% in 2013-14. IVE was particularly low among elderly in seasons dominated by the A(H3N2) viruses; it was 10% in 2011-12 and 2016-17 in people aged ≥80 years. Our results suggest a low to moderate IVE against influenza hospitalisation in adults. Evaluating complementary prevention options, such as prophylactic antiviral use, vaccination of health care workers and non-pharmaceutical interventions should be a priority.


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Affiliations:


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Hal:tel-01635265

Le document en format XML

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<title xml:lang="en">Post authorisation influenza vaccine effectiveness against influenza associated hospitalisation with laboratory confirmed influenza among adults in Europe</title>
<title xml:lang="fr">Efficacité post autorisation de mise sur le marché de la vaccination antigrippale saisonnière contre l’hospitalisation avec une grippe confirmée virologiquement chez l’adulte en Europe</title>
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<p>Our objective was to measure seasonal influenza vaccine effectiveness (IVE) against hospitalisation with laboratory-confirmed influenza in Europe among adults. Between 2011 and 2017, we coordinated a multicenter case-control study in 29 hospitals in 12 countries. We pooled and analysed the data after every season. Between 2011-12 and 2016-17, we recruited 3436 influenza cases and 5969 controls. Pooled across seasons, IVE against any influenza was 26%; 40% patients aged 18-64 yeas, 25% among those aged 65-79 years, and 23% among those aged ≥80 years. Season specific IVE ranged between 15% in 2016-17 and 44% in 2013-14. IVE was particularly low among elderly in seasons dominated by the A(H3N2) viruses; it was 10% in 2011-12 and 2016-17 in people aged ≥80 years. Our results suggest a low to moderate IVE against influenza hospitalisation in adults. Evaluating complementary prevention options, such as prophylactic antiviral use, vaccination of health care workers and non-pharmaceutical interventions should be a priority.</p>
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Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/France/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000039 | SxmlIndent | more

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HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000039 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    H2N2V1
   |flux=    France
   |étape=   Analysis
   |type=    RBID
   |clé=     Hal:tel-01635265
   |texte=   Post authorisation influenza vaccine effectiveness against influenza associated hospitalisation with laboratory confirmed influenza among adults in Europe
}}

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Data generation: Tue Apr 14 19:59:40 2020. Site generation: Thu Mar 25 15:38:26 2021